Contributors: Sarah Windle and Crystal Sequeira contributed equally as joint first authors. Sarah Windle, Mark Eisenberg and Kristian Filion contributed to the conception and design canada cannabis edibles law of the work. Sarah Windle and Crystal Sequeira jointly drafted the manuscript. All of the authors revised the manuscript for important intellectual content, gave final approval of the version to be published and agreed to be accountable for all aspects of the work. What hasstuck out to him so far, however, is that many of the concerns around legalized cannabis— including potential increased cases of cannabis-induced psychosis and schizophrenia, and driving under the influence of drugs — have notmaterialized. In Canada, prudent regulatory and public health measures to deter cannabis-impaired driving may be able to prevent increases in cannabis-impaired driving and its consequences since the legalization of recreational cannabis. However, a multi-disciplinary response is required for optimal detection and deterrence. 15 Substantial uncertainty exists concerning the optimal use of available measures and tools for detecting cannabis-impaired driving.2